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I'd say it really depends on the system you are using!
If there is no chest ascender (or some devive high up in front of you) I'd go as low as it gets with the hand ascender. No reason to work over head if you dont have to, we do it enough in other situations...
And dont forget to take small steps, it makes the system more efficient and better for your knees!
Preferably you shouldnt bend the knee not more than 90°, I do even less in my system...
Its so sad still seeing people with badly adjusted setups wasting some of the advantages of SRT ascent...
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Agreed, it's totally unique per individual and system. Some climbers like a big step per stroke, others like a small step. Best thing to do is make a simple adjustable footloop to test. For example use some say 10mm cordage to make the footloop, create the loop with a Bowline, try it out, adjust the length til you like it for a particular SRT setup.
-AJ