The ISC RP050 is rated for 1/2" rope. The Pinto pulley is rated for 9/16". Here they are side by side.
I often feel that the standard answer to any gear question "just follow manufacturer recommendations" is a bit of a cop-out. It's obviously the safest, most vanilla answer. It challenges no one. It offends no one. It also helps no one, because everybody already knows it. But how much of manufacturer recommendations are based on objective facts, and how much are based on subjective boardroom opinions? How can you know if the manufacturer is pushing the limits of what is possible, or being safe and conservative?
To the original question, I use 9/16" in 1/2" blocks quite a bit without issue (but not omni-blocks). Then again, it's only in overhead rigging. I use rings for all my negative rigging. As always, "follow manufacturer recommendations"