All living things have a sentience. Some organisms are harder to understand than others, but as far as I can tell, life is life. Karma is simply action and it's subsequent consequences. Cause and effect. There is no "good" or "bad" Karma per se. I sometimes get into this a bit aggressively when Vegans try to get high and mighty with me.
You can't avoid Karma, except by not doing anything. If you don't breathe, I am pretty sure you will die, and there are microbes floating in the air that will die inside of you after you inhale them, so there's that. I think that the Karmic elements are fairly clear, and I respect the notion of never killing a tree.
My Karma is such that I still enact other people's desires to have a tree removed. I feel like that's more on them than me, but we all play our part.
You feelin' bad about cutting down that tree last week?